Variability of colonial morphology in benomyl-induced morphological mutants from Candida albicans
نویسندگان
چکیده
منابع مشابه
Genetic analysis of Candida albicans morphological mutants.
In contrast to some other strains, Candida albicans 1001 gave rise, upon UV irradiation, to mutants displaying a 'rough colony' morphology associated with a permanent alteration in morphogenesis which determined growth of the cells mostly as pseudohyphae. One of these mutants, C. albicans 1001FR, could form sectored (rough/smooth) colonies spontaneously, and with increasing frequency by treatme...
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Biofilm formation plays a key role in the life cycles and subsistence of many microorganisms. For the human fungal pathogen Candida albicans, biofilm development is arguably a virulence trait, because medical implants that serve as biofilm substrates are significant risk factors for infection. The development of C. albicans biofilms in vitro proceeds through an early phase, in which yeast cells...
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Mutants of Candida albicans resistant to aculeacin A, a yeast cell-wall inhibitor, were isolated after mutagenesis with ultraviolet light. The parental strain was sensitive to 0.1 approximately 0.5 microgram/ml of the antibiotic. In contrast, the minimum inhibitory concentration for the mutants ranged from 50 to 200 microgram/ml. Except for papulocandin, another cell-wall inhibitor, the antibio...
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The ultrastructures of colonies of two stable UV-induced morphological mutants and their parental strain of Candida albicans grown on glucose-containing solid medium were investigated by scanning electron microscopy. The structures and ultrastructures of these three types of colonies were determined not only in terms of the proportions of blastospores, hyphae and pseudohyphae, but also with reg...
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Benomyl treatment (at 100 micrograms ml-1) of Candida albicans 1001, and other strains derived from it, determined the appearance of morphological mutants similar to those derived from UV irradiation treatment. A permanent alteration in the morphogenesis of these mutant strains determined their inability to grow by budding, to form oval yeast cells or blastospores (Y-phenotype) and their growth...
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ژورنال
عنوان ژورنال: FEMS Microbiology Letters
سال: 1987
ISSN: 0378-1097
DOI: 10.1016/0378-1097(87)90172-8